Endocrine Abstracts

The aim of our study was to assess the advantage of combinative therapy with lisinopril and moxonidin for the treatment of arterial hypertension in group of obese patients in comparison to the single-drug therapy with lisinopril.Methods: 26 obese patients were divided in 2 groups. They underwent a 24-hour monitoring of the arterial pressure and were diagnosed as arterial hypertension II degree (ESH-ESC). In the I group for the purpose of stabiliza...

We have investigated the leptin production by total and regional fat mass in 32 overweight postmenopausal women as well as the relation between serum leptin levels, total body fat mass and body fat distribution variables. Body mass index (BMI) was calculated in kg/m2. Serum concentrations of leptin were evaluated by RIA. Body composition – trunk/total, arms+legs/total+legs/trunk, android/gynoid ratios were assessed by dual-energy X-ray absorptiometry (DEXA). Th...

Background: The aim of our study was to assess the effectiveness of α-lipoic acid for the reducing the risk of developing peripheral diabetic neuropathy.Subjects and methods: We have studied 38 patients with type I and II diabetes, from age 28 to 35. The mean duration of disease was 9 years. Patients were divided in two groups. In group I were included 15 patients which got α-lipoic acid in order to prevent peripheral diabetic neuropathy in dos...

Background: The cardiovascular complication is the main cause of morbidity and mortality in obese patients. Endothelial dysfunction and atherosclerosis have the goal role in development of these diseases. The aim of our study was to reveal the role of nitric oxide during obesity associated arterial hypertension.Subject and method: 200 obese patients (age 35–55) were investigated. Control group comprised 25 healthy subjects. We calculated BMI, determ...